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Prajapati, Parimal M.
- Caco-2 Cell-A New Vision in Cell World
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Authors
Affiliations
1 Shukla Institute of Pharmaceutical Education & Research, Gujarat Technological University, Behind Marketing Yard, Nr. Lalpari Lake, Amargadh (Bhichari), Rajkot, Gujarat, IN
2 I. K. Patel College of Pharmaceutical Education and Research, Samarth Campus, Opp. Sabar Dairy, Himmatnagar-383001, Sabarkantha, Gujarat, IN
3 Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Hemchandracharya North Gujarat University, Arvind Baug, Mehsana-384001, Gujarat, IN
1 Shukla Institute of Pharmaceutical Education & Research, Gujarat Technological University, Behind Marketing Yard, Nr. Lalpari Lake, Amargadh (Bhichari), Rajkot, Gujarat, IN
2 I. K. Patel College of Pharmaceutical Education and Research, Samarth Campus, Opp. Sabar Dairy, Himmatnagar-383001, Sabarkantha, Gujarat, IN
3 Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Hemchandracharya North Gujarat University, Arvind Baug, Mehsana-384001, Gujarat, IN
Source
Research Journal of Science and Technology, Vol 3, No 2 (2011), Pagination: 51-54Abstract
Caco-2 cells are most commonly used not as individual cells, but as a confluent monolayer on a cell culture insert filter (e.g., Transwell). When cultured in this format, the cells differentiate to form a polarized epithelial cell monolayer that provides a physical and biochemical barrier to the passage of ions and small molecules. The Caco-2 monolayer is widely used across the pharmaceutical industry as an in-vitro model of the human small intestinal mucosa to predict the absorption of orally administered drugs. The correlation between the in vitro apparent permeability (PĀ¬app) across Caco-2 monolayers and the in-vivo fraction absorbed (fa) is well established.- Green Chemistry:A New Way to Prevent Environmental Pollution
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Authors
Affiliations
1 Department of Pharmaceutical Chemistry, I. K. Patel College of Pharmaceutical Education and Research, Samarth Campus Opp. Sabar Dairy, Himatnagar, Dist S.K. Gujarat, IN
2 Department of Pharmaceutical Chemistry, I. K. Patel College of Pharmaceutical Education and Research, Samarth Campus, Opp. Sabar Dairy, Himatnagar, Dist: S.K. Gujarat, IN
1 Department of Pharmaceutical Chemistry, I. K. Patel College of Pharmaceutical Education and Research, Samarth Campus Opp. Sabar Dairy, Himatnagar, Dist S.K. Gujarat, IN
2 Department of Pharmaceutical Chemistry, I. K. Patel College of Pharmaceutical Education and Research, Samarth Campus, Opp. Sabar Dairy, Himatnagar, Dist: S.K. Gujarat, IN
Source
Research Journal of Science and Technology, Vol 3, No 1 (2011), Pagination: 12-16Abstract
Green Chemistry includes such concepts as waste minimization, solvent selection, atom utilization, intensive processing and alternative synthetic routes from sustainable resources. The challenge for chemists is to develop products, processes and services in a sustainable manner to improve quality of life, the natural environment and industry competitiveness. Green Chemistry issues are here to stay. The most successful chemical companies of the future will be those who exploit its opportunities to their competitive advantage, and the most successful chemists of the future will be those who use Green Chemistry concepts in R and D innovation and education. As a chemical philosophy, green chemistry derives from organic chemistry, inorganic chemistry, biochemistry, analytical chemistry, and even physical chemistry. However, the philosophy of green chemistry tends to focus on industrial applications. The focus is on minimizing the hazard and maximizing the efficiency of any chemical choice. It is distinct from environmental chemistry which focuses on chemical phenomena in the environment. Use of supercritical carbon dioxide as green solvent, aqueous hydrogen peroxide for clean oxidations and the use of hydrogen in asymmetric synthesis.Keywords
Green Chemistry, Green Solvent.- Artificial Neural Network:A New Approach for QSAR Study
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Authors
Affiliations
1 I. K. Patel College of Pharmaceutical Education and Research, Samarth Campus, Opp. Sabar Dairy, Himmatnagar-383001, Sabarkantha, Gujarat, IN
2 Shree H. N. Shukla Institute of Pharmaceutical Education and Research, Behind Marketing Yard, Nr. Lalpari Lake, Amargadh (Bhichari), Rajkot, Gujarat, IN
3 Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Hemchandracharya North Gujarat University, Arvind Baug, Mehsana-384001, Gujarat, IN
1 I. K. Patel College of Pharmaceutical Education and Research, Samarth Campus, Opp. Sabar Dairy, Himmatnagar-383001, Sabarkantha, Gujarat, IN
2 Shree H. N. Shukla Institute of Pharmaceutical Education and Research, Behind Marketing Yard, Nr. Lalpari Lake, Amargadh (Bhichari), Rajkot, Gujarat, IN
3 Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Hemchandracharya North Gujarat University, Arvind Baug, Mehsana-384001, Gujarat, IN